If you are receiving error "The specified module could not be found." then try to instead of "C:Program FilesPHPphp5isapi.dll" write C:Progra~1PHPphp5isapi.dll (without quotes) in Web Sites node, and in Default Web Site node, or any other. Right -> Properties -> Home Directory -> Cofiguration, find .php and click edit.
Also,extension are now in C:Program FilesPHPext, so if you are using MS SQL PHP extension for MS SQL then you will need manually to copy files php_sqlsrv_ts.dll and php_sqlsrv.dll to that folder.
ĂÂ Taken from my brain :P